JSurg

Meta-analysis of randomized, controlled clinical trials of antibiotic prophylaxis in biliary tract surgery.

Br J Surg. 1990 Mar;77(3):283-90

Authors: Meijer WS, Schmitz PI, Jeekel J

In this study all available clinical trials of antibiotic prophylaxis in biliary tract surgery, published from 1965 to 1988, were examined. Results of 42 randomized, controlled trials (4129 patients), in which a group of patients treated with antibiotics was compared with a group of patients not treated with antibiotics, were pooled. Wound infection rates in the control groups range from 3 to 47 per cent and are 15 per cent overall. The overall difference in infection rates is 9 per cent in favour of antibiotic treatment (95 per cent confidence interval 7-11 per cent), while the common odds ratio is 0.30 (95 per cent confidence interval 0.23-0.38). Subgroup meta-analysis showed a significant stronger protective effect in high risk patients, while the timing of wound inspection (i.e. early in hospital or late at follow-up) markedly influenced the treatment effect reported. Comparison of wound infection rates in patients treated with first generation versus second or third generation cephalosporins (11 trials, 1128 patients), as well as single-dose versus multiple-dose regimens (15 trials, 1226 patients) did not reveal any significant effect (P greater than 0.05) in each trial separately as well as in the overall comparison. The results indicate that there is evidence against further use of no-treatment controls and that the choice of treatment regimen can largely be made on the basis of cost.

PMID: 2138925 [PubMed - indexed for MEDLINE]

Meta-analysis of randomized controlled trials on the safety and effectiveness of early versus delayed laparoscopic cholecystectomy for acute cholecystitis.

Br J Surg. 2010 Mar 4;97(4):624

Authors: Gurusamy K, Samraj K, Gluud C, Wilson E, Davidson BR

The original article to which this Erratum refers was published in British Journal of Surgery 2010; 97: 141-150.

PMID: 20205210 [PubMed - as supplied by publisher]

Pre-transplant Overweight and Obesity Do Not Affect Physical Quality of Life after Kidney Transplantation.

J Am Coll Surg. 2010 Mar;210(3):336-344

Authors: Zaydfudim V, Feurer ID, Moore DR, Moore DE, Pinson CW, Shaffer D

BACKGROUND: Recent studies demonstrate that obesity does not affect survival after kidney transplantation. However, overweight and obesity impair health-related quality of life (HRQOL) in patients with chronic illnesses. We wished to examine the effects of pre-transplant overweight and obesity on post-transplant physical HRQOL in kidney transplant recipients. STUDY DESIGN: Patient-reported HRQOL data were systematically collected in kidney transplant recipients receiving post-transplant follow-up at Vanderbilt Transplant Center. Patients who received kidney transplants between 1998 and 2008, had at least 1 post-transplant physical component summary (PCS) measurement, and did not receive other solid organ transplants were included in this retrospective cohort study. Pre-transplant body mass index was stratified as normal, overweight, obese class I, and obese class II/extremely obese. HRQOL was measured primarily with the PCS scale of the Medical Outcomes Study Short Form 36 Health Survey. Multivariate linear and logistic regression models were used to test the effects of body mass index and demographic and clinical covariates on post-transplant HRQOL. RESULTS: The study cohort included 464 adults (mean body mass index 27.5 +/- 5.1; range 18.5 to 47.4). After controlling for gender (p = 0.148), pre-transplant dialysis (p = 0.003), previous kidney transplantation (p = 0.255), donor type (p = 0.455), steroid avoidance immunosuppression (p = 0.070), and follow-up time (p = 0.352), there was no effect of pre-transplant overweight or obesity on post-transplant PCS (all p >/= 0.112). Kidney transplant recipients who did not require dialysis pre-transplant and those who were managed with steroid avoidance after transplantation were more likely to achieve post-transplant PCS scores at or above the general population average (both p </= 0.011). CONCLUSIONS: Pre-transplant overweight and obesity do not affect physical quality of life after kidney transplantation.

PMID: 20193898 [PubMed - as supplied by publisher]

Proximal Esophageal pH Monitoring: Improved Definition of Normal Values and Determination of a Composite pH Score.

J Am Coll Surg. 2010 Mar;210(3):345-350

Authors: Ayazi S, Hagen JA, Zehetner J, Oezcelik A, Abate E, Kohn GP, Sohn HJ, Lipham JC, Demeester SR, Demeester TR

BACKGROUND: Patients with respiratory and laryngeal symptoms are commonly referred for evaluation of reflux disease as a potential cause. Dual-probe pH monitoring is often performed, although data on normal acid exposure in the proximal esophagus are limited because of the small number of normal subjects and inconsistent placement of the proximal pH sensor in relation to the upper esophageal sphincter. We measured proximal esophageal acid exposure using dual-probe pH and calculated a composite pH score in a large number of asymptomatic volunteers to better define normal values. STUDY DESIGN: Eighty-one normal subjects free of reflux, laryngeal, or respiratory symptoms were recruited. All had video esophagraphy to exclude hiatal hernia. Esophageal pH monitoring was performed using 1 of 3 different dual-probe catheters with sensors spaced 10, 15, or 18 cm apart. The standard components of esophageal acid exposure were measured, excluding meal periods. A composite pH score for the proximal esophagus was calculated using these components. RESULTS: The final study population consisted of 59 (49% male) subjects, with a median age of 27 years. All had normal distal esophageal acid exposure and no hiatal hernia. The 95(th) percentile values for the percent time the pH was < 4 for the total, upright, and supine periods were 0.9%, 1.2%, and 0.4%, respectively. The 95(th) percentile for the number of reflux episodes was 24 and for the calculated proximal esophageal composite pH score was 16.4. CONCLUSIONS: In a large population of normal subjects, we have defined the normal values and calculated a composite pH score for proximal esophageal acid exposure. The total percent time pH < 4 was similar to previously published normal values, but the number of reflux episodes was greater.

PMID: 20193899 [PubMed - as supplied by publisher]

Short-term outcomes from a prospective randomized trial comparing laparoscopic and open surgery for colorectal cancer.

Br J Surg. 2010 Mar 4;97(4):624

Authors: Neudecker J, Klein F, Bittner R, Carus T, Stroux A, Schwenk W,

The original article to which this Corrigendum refers was published in British Journal of Surgery 2009; 96: 1458-1467.

PMID: 20205211 [PubMed - as supplied by publisher]

Nanotechnology and its applications in surgery.

Br J Surg. 2010 Mar 4;97(4):463-465

Authors: Loizidou M, Seifalian AM

PMID: 20205212 [PubMed - as supplied by publisher]

Authors’ reply: Meta-analysis of randomized controlled trials comparing laparoscopic with open mesh repair of recurrent inguinal hernia (Br J Surg 2010; 97: 4-11).

Br J Surg. 2010 Mar 4;97(4):621-622

Authors: Karthikesalingam A, Markar S, Holt P, Praseedom R

PMID: 20205213 [PubMed - as supplied by publisher]

Treatment options for squamous cell cancer of the esophagus: a systematic review of the literature.

J Am Coll Surg. 2010 Mar;210(3):351-9

Authors: Kranzfelder M, Büchler P, Lange K, Friess H

PMID: 20193900 [PubMed - in process]

Primary chest wall tumors.

J Am Coll Surg. 2010 Mar;210(3):360-6

Authors: Shah AA, D’Amico TA

PMID: 20193901 [PubMed - in process]

Sealants after axillary lymph node dissection.

Am J Surg. 2010 Mar 2;

Authors: Hidar S, Bouguizane S, Regaya LB, Bibi M, Khairi H

PMID: 20202620 [PubMed - as supplied by publisher]

Reliable preparation of the gastric tube for cervical esophagogastrostomy after esophagectomy for esophageal cancer.

Am J Surg. 2010 Mar 2;

Authors: Matsuda T, Kaneda K, Takamatsu M, Takahashi M, Aishin K, Awazu M, Okamoto A, Kawaguchi K

Maintaining sufficient blood flow to the gastric tube is essential to avoid anastomotic leakage after esophageal reconstruction for esophageal cancer. We were able to obtain sufficient blood flow to the tip of the gastric tube by separating the inferior polar branches of the splenic vessels at their origin. By using this procedure, we were able to preserve the junction between the left gastroepiploic vessels and the inferior short gastric vessels without splenectomy. The entire greater omentum also was preserved to use the network between the right and left gastroepiploic vessels. Finally, the anastomotic site was wrapped with the omentum. By using these techniques, the anastomotic site of the gastric tube was well nourished in all patients who underwent esophageal reconstruction for esophageal cancer; anastomotic leakage did not occur.

PMID: 20202621 [PubMed - as supplied by publisher]

Letter 3: Meta-analysis of randomized controlled trials comparing laparoscopic with open mesh repair of recurrent inguinal hernia (Br J Surg 2010; 97: 4-11).

Br J Surg. 2010 Mar 4;97(4):621

Authors: Kurzer M, Hussain ST

PMID: 20205214 [PubMed - as supplied by publisher]

Letter 2: Meta-analysis of randomized controlled trials comparing laparoscopic with open mesh repair of recurrent inguinal hernia (Br J Surg 2010; 97: 4-11).

Br J Surg. 2010 Mar 4;97(4):621

Authors: Kumar S

PMID: 20205215 [PubMed - as supplied by publisher]

Letter 1: Meta-analysis of randomized controlled trials comparing laparoscopic with open mesh repair of recurrent inguinal hernia (Br J Surg 2010; 97: 4-11).

Br J Surg. 2010 Mar 4;97(4):620

Authors: Sgourakis G, Dedemadi G

PMID: 20205216 [PubMed - as supplied by publisher]

Authors’ reply: Randomized clinical trial comparing laparoscopic and open surgery in patients with rectal cancer (Br J Surg 2009; 96: 982-989).

Br J Surg. 2010 Mar 4;97(4):620

Authors: Lujan J, Valero G, Hernandez Q, Sanchez A, Frutos MD, Parrilla P

PMID: 20205217 [PubMed - as supplied by publisher]

Authors’ reply: Endoscopic retroperitoneal neurectomy for chronic pain after groin surgery (Br J Surg 2009; 96: 1076-1081).

Br J Surg. 2010 Mar 4;97(4):618-619

Authors: Giger U, Krähenbühl L

PMID: 20205218 [PubMed - as supplied by publisher]

Endoscopic retroperitoneal neurectomy for chronic pain after groin surgery (Br J Surg 2009; 96: 1076-1081).

Br J Surg. 2010 Mar 4;97(4):618

Authors: Vuilleumier H, Hübner M, Demartines N

PMID: 20205219 [PubMed - as supplied by publisher]

Author’s reply: Nationwide study of early outcomes after incisional hernia repair (Br J Surg 2009; 96: 1452-1457).

Br J Surg. 2010 Mar 4;97(4):618

Authors: Bisgaard T

PMID: 20205220 [PubMed - as supplied by publisher]

Nationwide study of early outcomes after incisional hernia repair (Br J Surg 2009; 96: 1452-1457).

Br J Surg. 2010 Mar 4;97(4):617-618

Authors: Jindal V, Khan RN, Panwar R, Bansal VK, Misra MC

PMID: 20205221 [PubMed - as supplied by publisher]

Authors’ reply: Systematic review of atraumatic splenic rupture (Br J Surg 2009; 96: 1114-1121).

Br J Surg. 2010 Mar 4;97(4):616-617

Authors: Renzulli P, Hostettler A, Schoepfer AM, Gloor B, Candinas D

PMID: 20205222 [PubMed - as supplied by publisher]